The drugs used in the treatment of rectal cancer are different according to the treatment plan. The drugs used by patients after rectal cancer surgery are mainly antibacterial drugs, enteral nutrition, parenteral nutrition, and drugs to protect the gastric mucosa. Such as cefoperazone sulbactam, metronidazole, carven, omeprazole, and corresponding blood products such as human albumin, plasma, and concentrated red blood cells. These drugs are beneficial to the patient’s postoperative recovery, as well as the healing of the anastomosis. For patients who need chemotherapy after or before surgery for rectal cancer, the drugs used are basically chemotherapy drugs based on 5-fluorouracil. The first is the 5-Fu regimen, which consists of oxaliplatin, calcium folinic acid, and 5-fluorouracil. The other regimen, the LV regimen, is oxaliplatin and Siroda, of which Siroda is administered orally. Given that chemotherapy drugs have certain side effects, adjuvant therapy is also given during chemotherapy. For example, granulocyte colony-stimulating factor for raising white blood cells, omeprazole for antiemetic, etc. If the patient’s resistance decreases during chemotherapy, immunity-enhancing drugs such as thymidine and EDI injection can be applied.