In the daily tests in the laboratory, it will be found that many people, not only diabetic patients, can have positive urine sugar, or what the people call a plus sign (++) in urine sugar. What is the significance of positive urine sugar? Who will have positive urine sugar? Positive urine glucose is mostly seen in diabetic patients who have elevated blood glucose that exceeds the renal load capacity, i.e., the renal glucose threshold is exceeded, and the urine glucose appears positive. Then, in non-diabetic conditions, there can also be positive urine glucose, for example, under physiological conditions, women in pregnancy, the kidney glucose threshold is lowered, there may be a new positive urine glucose; elderly people, the kidney function of physiological decline, there may also be positive urine glucose. There is also a small number of people who eat a lot of sugary foods, can also appear temporary positive urine sugar. In addition, oral intake of some drugs, such as diuretics, cephalosporin antibiotics, vitamin C, etc. can cause a positive urine sugar result. What is the significance of a positive urine sugar? For non-diabetic patients, a positive urine sugar is nothing to worry about as long as the cause is found, or if the urine sugar is occasionally positive, it can be reviewed regularly. For diabetic patients, positive urine sugar indicates that the patient’s blood sugar level is too high and exceeds the kidney load capacity, generally speaking, the blood sugar level should be above 10 mmol/L. Some people’s urine sugar disappears quickly after the blood sugar is lowered, but in some elderly people, even if the blood sugar is lowered, the urine sugar is still positive. This is because elderly patients have a reduced renal glucose threshold and even normal blood glucose levels exceed the kidney load capacity, resulting in positive urine sugar. Therefore, in clinical practice, it is not necessary to pay too much attention to the urine sugar result, and the diagnosis of diabetes cannot be made on the basis of the urine sugar result alone, nor can the effect of diabetes treatment be judged by the urine sugar result alone.