There are often many Parkinson’s disease patients who say they feel fatigued easily, tired, sit for a while and then confused, chatting and do not want to move. Some family members report that the patient is tired after a few minutes of exercise, and the whole body feels fatigue, and then they do not want to move. Normal people who exercise a lot will also have fatigue, for Parkinson’s disease patients, it is required to be appropriate exercise, or professional exercise, because Parkinson’s disease limb trembling, muscle stiffness, slow movement and posture and gait abnormalities, etc., can be involved in the whole body. The same movement requires more energy than normal to accomplish in Parkinson’s disease, and the patient’s muscles are more likely to feel fatigued. Fatigue is an important but often overlooked symptom in Parkinson’s disease (PD) patients, with previous studies showing its prevalence ranging from 33% to 58%, and it is considered one of the most important symptoms affecting the quality of life of PD patients and leading to disability. So how can fatigue symptoms be improved or alleviated? For motor fatigue, commonly used anti-Parkinson’s disease medications can improve motor symptoms or have some effect; some patients are fatigued due to some depression, anxiety, apathy, sleep disorders and other diseases, which need to be treated by other medical means. If necessary, DBS surgery can be performed to control the symptoms of Parkinson’s disease, thus relieving the patient’s fatigue symptoms. Some other small ways to help relieve the symptoms of fatigue: 1, at home, let the family give more support, share more chores, do some of your own chores that you can do; 2, try and stick to some hobbies, arrange the activities every day, help to avoid feeling fatigue in the daytime; you can try to exercise, no matter what the situation causing fatigue, exercise exercise seems to be the only one universal and effective method, many patients said that they feel energized after moderate exercise instead. For exercise fatigue, commonly used anti-Parkinson’s disease medications because they can improve motor symptoms or have some effect; some patients have fatigue due to some depression, anxiety, apathy, sleep disorders, and other disorders, which need to be treated by other medical means.