Possible reasons for not wanting to eat without appetite include gastrointestinal dysfunction, ulcerative diseases, and vegetative nerve dysfunction. 1. Gastrointestinal dysfunction: dysbiosis in the intestinal tract, cold, lack of trace elements such as iron, zinc and other reasons may lead to gastrointestinal dysfunction, intestinal peristalsis slows down, resulting in indigestion, constipation, etc., and thus patients experience symptoms of loss of appetite. 2. Ulcerative diseases: large amounts of alcohol, overeating, drugs, Helicobacter pylori infection and other factors lead to gastrointestinal ulcers, such as gastric ulcers, duodenal ulcers, etc., which can lead to a decline in gastrointestinal function, gastric distension, stomach pain before or after meals, nausea, etc., which can also lead to the patient’s symptoms of not wanting to eat, no appetite. 3. Phytoneurological dysfunction: when there is long-term mental tension, psychological stress, insomnia, fatigue, etc., it can lead to the body’s phytoneurological dysfunction, which in turn triggers gastrointestinal dysfunction and the symptoms of loss of appetite. Loss of appetite may also have other reasons, when long-term symptoms of loss of appetite, it is recommended to go to the regular hospital in a timely manner to identify the causes and active treatment.