Metformin enteric-coated tablets are glucose-lowering medications used to treat diabetes mellitus, and the side effects are mainly gastrointestinal symptoms, such as nausea, diarrhea, and abdominal pain. Metformin enteric-coated tablets are glucose-lowering drugs used for type 2 diabetes mellitus that is not satisfactorily controlled by diet and exercise. Side effects include nausea, vomiting, abdominal pain, diarrhea, bloating, constipation, abnormal taste, weakness, rash, and itching. Metformin is contraindicated in patients with renal failure, severe infections and trauma, diabetic coma prodrome, hepatic insufficiency, acute alcoholism, vitamin B12 and folic acid deficiency. Metformin enteric-coated tablets need to be used under medical supervision.