Big toe jiggling on its own mostly refers to involuntary jiggling of the big toe, and the possible causes are tension, exertion, lack of calcium in the body, Parkinson’s syndrome and so on. 1. Tension: Because of excessive emotional tension and involuntary muscle contraction, big toe jiggling may occur, you can properly relax and eliminate tension. 2. Exhaustion: because of strenuous exercise, long-distance running, long-time standing activities and other factors, resulting in muscle tension contracture, there will also be involuntary shaking, which is a normal phenomenon, generally can be relieved after rest. 3. Calcium deficiency: Due to insufficient calcium intake and absorption by partial feeding or excessive calcium loss caused by thyroid disease, etc., the nerve excitability increases after the calcium ion content decreases, and the muscles reactive contraction, which can lead to big toe shaking. 4. Parkinson’s syndrome: due to abnormal nerve function, involuntary body tremor can occur, which can be accompanied by slow movement, slow speech and other symptoms. There are many reasons for involuntary trembling of the big toe, and it may also be related to epilepsy, muscle injury and other diseases. If the symptoms continue to be unrelieved, it is recommended to consult a doctor in time to clarify the cause of the disease and carry out targeted treatment.