AS is short for ankylosing spondylitis, which is a disease of the rheumatic immune system. There are several reasons why ankylosing spondylitis arises. The first is an infection, which can be caused by a microorganism that can easily lead to ankylosing spondylitis. The second cause is genetic, which can be passed on to the next generation through the previous generation. In addition, a humid and dark environment in daily life can also lead to an increase in the incidence of ankylosing spondylitis. The symptoms of ankylosing spondylitis are usually non-specific in the early stages, such as wasting, weakness, loss of appetite, indigestion, anemia, etc. Gradually, the disease invades the sacroiliac joints, producing sacroiliac arthritis, and invades the spine, leading to spinal ankylosis. In the end stage of the disease, the heart valves, eyes and kidneys can also be affected. Treatment is based on non-steroidal anti-inflammatory drugs, glucocorticoids, chemotherapy drugs and biological agents.