Case: He is 40 years old, has a 14-year-old son, has a wife whom he doesn’t love, and is still taking “Bolehyn” prescribed by a psychiatrist. Although he has been taking this medicine for more than one year, he always thinks that the medicine can not solve his thought problem, and he is very anxious when he encounters anything, and now he can not work, and he has lost his social function, and any work will make him feel anxious, and he can not last long. Through exchanges, learned that when he was a child, under his father’s strict discipline, afraid of contact with strangers, they are afraid to make decisions on major issues, and now do nothing is not interested in doing anything, they feel that they have been abandoned by the world, and often inexplicable nervousness, no one can understand himself, and from time to time have the idea of ending their own lives. In 10 days ago ran away from home, was forced to bring his sister’s sister’s home. So depression in addition to medication there are those means of treatment? 1, drug treatment Drug treatment is the main treatment measure for depression episodes above moderate. At present, the first-line antidepressants mainly include selective 5-hydroxytryptamine uptake inhibitors (SSRI, representative drugs fluoxetine, paroxetine, sertraline, fluvoxamine, citalopram and escitalopram), 5-hydroxytryptamine and norepinephrine re-uptake inhibitors, norepinephrine, and specific 5-hydroxytryptamine antidepressant drugs (NaSSA, representative drugs m-zolpidem) and so on. Mirtazapine), etc. Traditional tricyclic and tetracyclic antidepressants as well as monoamine oxidase inhibitors have been significantly reduced due to their adverse reactions. Psychotherapy For patients with depression who have obvious psychosocial factors, it is often necessary to combine psychotherapy with drug treatment. Commonly used psychotherapeutic methods include supportive psychotherapy, cognitive behavioral therapy, interpersonal therapy, marriage and family therapy, psychodynamic therapy, etc., in which the efficacy of cognitive behavioral therapy for depressive episodes has been recognized. 3.Physical therapy Patients with serious negative suicide attempts and patients who are not treated with antidepressants can be treated with modified electroconvulsive therapy (MECT). After the electroconvulsive treatment, medication is still needed to maintain the treatment. In recent years, there is a new physical therapy – Repetitive Transcranial Magnetic Stimulation (rTMS) therapy, which is mainly applicable to mild to moderate depressive episodes. 4, sunshine therapy Sunshine is a very good medicine for depression, most suitable for the treatment of seasonal nature of depression. Many people’s symptoms develop during the change of seasons, which are characterized by apathy, listlessness, and decreased work efficiency, which will gradually disappear under the light of the sun. 5, sports therapy Exercise is a good way to resist inhibition, a large number of studies show that exercise, especially aerobic exercise, help eliminate mild depression. 76-year-old Chuck every day to insist on playing basketball with people half or less than he is small. If I don’t exercise five times a week, I start to become bored with life, he says. The perseverance I get from exercise makes me optimistic about life. 6, psychological therapy Patients should affirm themselves in time, every night before going to bed, to fully affirm their own achievements of this upcoming past day as well as progress, do not talk about negative things. It is best to keep a diary and write down the good experiences, progress and achievements in the diary. If you keep a diary every day, you will find life more and more interesting. 7, group therapy Patients should establish reliable interpersonal relationships, no matter what happens, there is a person who can be completely trusted, whether it is a relative, a spouse or a friend, is one of the most important guarantees to prevent depression, do not tell negative things to friends and relatives, friends and relatives do not listen to the patient’s negative talk, the main thing is that friends and relatives listen to the patient talk about negative things, it will strengthen them to like to talk about negative things.