The sequelae of brainstem hemorrhage can include deep coma, vegetative state, limb function limitation, sensory limitation, speech impairment, electrolyte disturbance, acidosis, and cerebral edema. The death rate of brainstem hemorrhage is still very high, and the death rate of elderly patients over 70 years old can be over 70%, but the younger the age, the lower the death rate. Brainstem hemorrhage develops rapidly and the symptoms of increased intracranial pressure appear early, so the sequelae are more serious for patients who do not die. If patients develop physical dysfunction, systematic rehabilitation is required. If language and swallowing function decline, corresponding targeted rehabilitation training is needed, and some patients may have cognitive function decline as well as cognitive function training. It is important to note that brainstem hemorrhage coma for a long time may lead to stiffness, atrophy, and relaxation of limbs, joints, and muscles and ligaments, all of which belong to the scope of rehabilitation training. For patients in deep coma, vital signs must be maintained, lung infections and urinary tract infections must be prevented, and patients should be turned regularly to avoid bedsores. The sequelae of brainstem hemorrhage are, in most cases, serious, so on the one hand, we have to wait for the absorption of the hematoma, on the other hand, we have to carry out targeted treatment for the sequelae of the patient, such as rehabilitation training, and also actively treat the primary disease.