Slightly large lymph node shadow found on imaging examination is not necessarily due to cancer, but may also be due to lymphadenitis, lymphatic tuberculosis, etc. Further pathologic examination is recommended. Lymph nodes are important immune tissues in the human body and have immune functions such as removing bacteria, storing and producing lymphocytes. Ultrasound and other imaging examinations of lymph nodes may reveal slightly larger lymph nodes, which may be caused by lymphadenitis, lymphatic tuberculosis, lymphatic primary tumors, or metastasis from other parts of the body, but not necessarily due to cancer. Enlarged lymph nodes caused by lymphadenitis or local infections are usually accompanied by fever, local pain and other manifestations, and a large number of inflammatory cells can be seen in pathological examination of lymph nodes. Lymph node enlargement caused by lymphatic tuberculosis may present with systemic symptoms, such as low-grade fever, night sweats, malaise, etc. Pathologic examination may show necrosis, etc., and Mycobacterium tuberculosis may be detected. Lymph node enlargement due to tumor usually develops continuously without obvious pain or pressure, and cancer cells can be seen on pathological examination. Imaging examination reveals a slightly larger lymph node shadow, and prompt consultation is recommended.