The swelling of the eyes after waking up may be caused by physiological factors, or it may be caused by conjunctivitis, blepharitis and other factors. 1. Physiological factors: If you drink a lot of water before going to bed, it may lead to water accumulation in the body can not be discharged, thus causing the situation of waking up with a swollen eye, generally do not need special treatment, full rest can be relieved on their own. But daily habits need to be adjusted to avoid drinking too much water before going to bed. 2. Conjunctivitis: Poor eye hygiene is susceptible to bacterial attack, and bacteria may multiply during sleep, thus stimulating the conjunctiva of the eye to cause inflammation, resulting in the symptom of waking up with swollen eyes. Pralofen eye drops, tobramycin dexamethasone eye drops and other medications can be used for treatment under the guidance of a doctor. 3. Blepharitis: usually caused by bacterial infection of the eyelid area, the inflammation will stimulate the eyelid area to congestion, edema, and thus the phenomenon of waking up with swollen eyes. You can use levofloxacin eye drops, ofloxacin eye ointment and other medications as prescribed by your doctor. After waking up with swollen eyes, exclude physiological factors, go to the hospital to clarify the cause of standardized treatment, do not blindly use their own medication.