Small bumps at the junction of the penis and foreskin may be the result of diseases such as genital herpes, condyloma acuminatum, and pearly penile papules. 1. Genital herpes: genital herpes is mainly caused by herpes simplex virus infection. Most patients with genital herpes do not have obvious signs and symptoms. Some patients may have blisters, vesicles, and ulcers around the genitals, which can be manifested as small bumps on the penis and the foreskin junction. 2. Condyloma acuminatum: Condyloma acuminatum is mainly caused by human papilloma virus infection. Patients can appear in the external genitalia reddish small particles, the tip is slightly sharp, with the development of the disease, can gradually increase, the form of papillary, cauliflower, etc., can be manifested in the penis and foreskin connection with small bumps. 3. Pearly penile papules: the cause of pearly penile papules is not yet clear, it may be caused by local irritation, long prepuce, poor personal hygiene habits and other factors. Patients can appear in the coronal groove of the penis pearly, translucent papules, which can be manifested as small bumps on the penis and foreskin connection. There are many reasons that cause patients to have small bumps on the penis and foreskin junction, it is recommended that patients go to regular hospitals, identify the cause of the disease and then treated under the guidance of doctors.