Hidden pain in the right upper abdomen at night more serious may be cholecystitis, cirrhosis, duodenal ulcer and other disease factors, can be targeted treatment under the guidance of the doctor, such as drug treatment, surgical treatment. 1. duodenal ulcer: there can be night pain, abdominal pain, can follow the doctor’s instructions to use omeprazole, lansoprazole and other acid-suppressing drugs, aluminum thioglycollate, Rebapatite and other gastric mucosal protection agent treatment. 2. Chronic cholecystitis: there may be symptoms of hidden pain in the right upper abdomen at night or after a full meal. Accompanied by epigastric pain can use pivacurium bromide for pain relief, acute attacks of biliary colic can use scopolamine for pain relief, accompanied by infection can use metronidazole and other antibiotic treatment, medical treatment is ineffective can be considered surgical treatment. 3. Cirrhosis: adenosylmethionine, reduced glutathione and other hepatoprotective drugs can be used to treat, with ascites can be used spironolactone, furosemide diuretic treatment, but also can be infused with albumin treatment. Hidden pain in the right upper abdomen, there are other reasons, the appearance of the above symptoms, it is recommended to go to the hospital, improve the examination, clarify the cause of the disease, symptomatic treatment.