What are the side effects of paclitaxel?

The side effects of paclitaxel include myelosuppression, gastrointestinal reactions, allergic reactions, cardiovascular reactions, and neurological abnormalities. Paclitaxel is a commonly used chemotherapeutic drug in oncology department, the side effects are as follows: 1. Bone marrow suppression: common neutropenia, thrombocytopenia, anemia. Patients with granulocytopenia are more likely to be complicated by infections, including pneumonia and peritonitis. 2. Gastrointestinal reactions: nausea, vomiting, diarrhea, abdominal pain are common; small bowel obstruction, intestinal perforation, pancreatitis, dehydration, esophagitis, constipation and ascites are occasionally seen. 3. Allergic reactions: facial flushing, skin rash, tachycardia in mild cases; respiratory distress, angioneurotic edema, hypotension, generalized urticaria in severe cases. 4. Cardiovascular system reactions: including syncope, arrhythmia, hypertension, venous thrombosis, ECG abnormalities. 5. Nervous system abnormalities: peripheral neuropathy, numbness of hands and feet, occasional convulsions, dizziness and headache can be seen. In addition, some patients may also have bilirubin and liver enzyme elevation, injection site edema, pain, phlebitis, alopecia, myalgia, arthralgia and other adverse reactions. The medication should be used under medical supervision.