Cephalosporin antibiotics and nitroimidazole antibiotics should not be taken after drinking alcohol because they have a special structure in their chemical structure that can produce a disulfiram-like reaction with alcohol. Patients may experience flushing, palpitations, chest tightness, shortness of breath, nausea, vomiting, hypotension, shock, cardiac arrhythmia, or even cardiac arrest, which can be life-threatening and therefore cephalosporins and nitroimidazoles should not be used after drinking alcohol. Cephalosporins include cefoperazone, cefminox, cefamandole and other cephalosporins, among which cefoperazone has been reported to produce the most disulfiram-like reactions. Nitroimidazole antibiotics include metronidazole, ornidazole, tinidazole, etc. The above mentioned drugs may be used if the patient has a lung infection, biliary infection or gum infection. It is recommended to ask if there is a history of alcohol consumption within a week before using the medication, if there is a history of alcohol consumption within a week, the above mentioned medication should not be applied. If you have not consumed alcohol, you should not consume alcohol within one week after the application of the above mentioned medication.