Feeling tired and heavy may be related to psychological factors, disease factors, physiological factors and so on. 1. Psychological factors: because of work pressure becomes bigger, or study pressure is too big, thus affecting the sleep, do not have a good rest, so that the body is in a state of fatigue, do not have the heart to study and work and thus feel very tired and heavy. 2. Disease factors: patients with depression are mainly characterized by low mood, pessimism, reduced interest, slow thinking, self-blame, poor diet and sleep, etc., and often feel very tired and heavy. It is suggested that it can be treated by drugs, such as Sulpiride tablets, Sertraline hydrochloride tablets, Paroxetine hydrochloride tablets and so on to relieve. 3. Physiological factors: may be due to frequent late nights plus overeating, thus appearing gastrointestinal functional lesions symptoms, which is manifested in the body is very tired especially heavy and so on. It is suggested that the treatment can be carried out through drugs, such as mosapride citrate tablets, domperidone tablets and so on. The above medications need to be treated under the guidance of a doctor to avoid adverse reactions and effects. At the same time, in daily life, we can also communicate more with patients or help patients to exercise effectively, and shape a better living environment to help relieve the pessimistic mood of patients. Make the patient full of energy, relaxation and thus reduce the mood of depression.