Nasopharyngeal biopsy for inflammation and immunohistochemistry for cancer are unlikely. Nasopharyngeal pathology biopsy is currently the most commonly used tumor test, and likewise one of the tests with the highest diagnostic accuracy. It can assist the clinic to make a diagnosis of the disease, or provide clues for the diagnosis of the disease. At the same time, it can also understand the nature and development trend of the tumor, so as to provide certain reference for the treatment of the tumor. Immunohistochemistry also plays an important role in the diagnosis and differential diagnosis of tumor. For example, the positive rate of immunohistochemical expression of breast lesion coarse needle aspiration minimally invasive biopsy and postoperative routine immunohistochemistry is consistent, and the difference is not statistically significant. The accuracy of both biopsy and immunohistochemistry was high. If nasopharyngeal pathology biopsy is inflammatory, immunohistochemistry is usually not cancerous.