Blackheads may be caused by excessive sebum production and abnormal keratinization of the sebaceous gland ducts of hair follicles. Blackheads can be removed through medication, acne squeezers, and fruit acid peels. 1. Excessive sebum secretion: sebaceous glands secrete large amounts of lipids, when the composition of lipids changes, such as squalene peroxide, wax esters, free fatty acid content increases, oxidized by oxygen, can cause the occurrence of blackheads. For this disease when the surrounding lesions are not infected, a special acne squeezer can be used to squeeze out the blackhead lipid plugs in the papules one by one. 2. Abnormal keratinization of follicular sebaceous gland ducts: Keratinization disorder of the cells in the funnel part of the hair follicle leads to accelerated disintegration, shedding and turnover of follicular keratinized cells, which results in the formation of microcomedones, and blackheads will appear when melanin is deposited. Medications can be chosen for treatment, such as retinoic acid cream and benzoyl peroxide ointment, which can improve the keratinization of follicular sebaceous gland ducts, dissolve microcomedones and acne, and anti-inflammatory effects. You can also choose fruit acid peeling, which has the effect of exfoliating, reducing follicle blockage as well as controlling oil, which can reduce and prevent the production of blackheads. The use of the above medications is subject to medical advice. It is recommended that patients with blackheads go to the hospital in a timely manner and follow the doctor’s instructions for relative treatment to avoid delays.