There is no major micronutrient that enhances caries resistance, but fluorine is the most important micronutrient that enhances caries resistance. Dental caries is a bacterial infectious disease, that is, oral microorganisms adhere to the tooth surface to form plaque biofilm, oral microorganisms in the plaque biofilm micro-ecological environment using sugar food metabolism to produce acid, and long-term accumulation on the surface of the tooth caused by enamel demineralization. Fluoride and hydroxyapatite have a special affinity, fluorine can directly enter the enamel, and hydroxyapatite, fluorine instead of hydroxyapatite in the hydroxyl group, the formation of acid-insoluble fluorapatite, to enhance the acid resistance of enamel. Fluorine can also inhibit the metabolism of acid-producing caries-causing teeth, thus inhibiting the acid-producing ability and metabolic activity of bacteria, and achieving the effect of caries prevention. You can choose fluoride toothpaste or mouthwash to prevent dental caries, but fluoride toothpaste can not replace the drug to treat dental caries, specific can consult the dentist.