It is possible for interferon shots to cause numbness in the feet. Interferon is a broad-spectrum antiviral drug with antiviral and immunity-regulating effects, but some patients may experience some side effects after taking interferon, such as nerve disorders, coma, numbness of limbs, etc., which involves the central nervous system and digestive system. Therefore, for some patients, interferon is possible to cause numbness of the feet phenomenon. Interferon is mostly used to treat viral hepatitis B and C. However, interferon does not kill the virus directly. However, interferon does not directly kill the virus, but can only inhibit viral replication, but also enhance the body’s immunity, can play a role in alleviating the disease. Patients who need to use interferon must be under the guidance of a doctor, in accordance with the scientific way of injection, the emergence of adverse reactions, the need to consult a doctor in a timely manner, in order to avoid delaying the condition.