Diabetic foot is a serious and widespread complication of diabetes mellitus. The incidence of diabetes mellitus is rapidly increasing year by year, and the incidence of diabetic foot has also increased dramatically. The conventional treatment strategy is to control blood sugar, nerve nutrition, improve circulation and anti-infection, trauma care, etc. Other methods, such as surgery, interventional therapy, stem cell transplantation, are still unsatisfactory, and many patients have to amputate their limbs in order to save their lives, however, Chinese medicine has unique advantages in promoting wound healing and reducing amputation. Chinese medicine believes that the main pathogenesis of diabetic foot is: deficiency of qi and blood, stasis of blood and congestion of heat toxins. If the wound is pale and dripping with water, it is necessary to nourish the qi and blood, such as Bajhen Tang with frankincense, myrrh and salvia, or Zhang Xichun’s Naito Sangmusan. If the patient has a foul-smelling wound, it is necessary to focus on activating the blood and clearing the heat and detoxification, such as Si Miao Yong An Tang. In clinical practice, if Chinese and Western medicine are combined to treat diabetic foot, it can not only improve the cure rate, reduce the hospitalization time, but also reduce the amputation rate of patients.