Instantaneous blistering of the tongue is usually caused by trauma, usually due to eating sharp or hard food, which can cause a pinch of the mucosa of the tongue, resulting in instantaneous blistering. The blisters can be extracted from the blister or cut with a razor blade at the stomatology department, and topical medication can be applied, such as iodoglycerin or drugs that promote healing, such as recombinant human epidermal growth factor gel or topical solutions, or appropriate stomatitis sprays or open throat sword sprays. In addition, instant blood blisters on the tongue may also be related to systemic diseases, mainly blood system diseases causing coagulation dysfunction such as leukemia, aplastic anemia, hemophilia, etc., will appear instant blood blisters on the tongue, should promptly go to the hospital to check the blood routine and coagulation function, after a clear diagnosis of systemic application of coagulant drugs or blood transfusion therapy. Instant blood blisters on the tongue is recommended to promptly visit the stomatology department for examination to avoid other sexual diseases.