Under normal circumstances if the total calorie intake of the body exceeds the total calorie consumption for a long time, weight gain will occur, so a reasonable way to lose weight is to reduce the total calorie intake and increase the total calorie consumption. The main points include the following: First, reduce calorie intake, by reducing the intake of carbohydrates and fats in the diet, avoiding high-fat diet, refined and processed foods, high-calorie foods and fried foods to reduce calorie intake. Second, increase the amount of exercise, exercise can improve insulin resistance, increase calorie consumption, so as to achieve the purpose of weight control. Third, regular weight monitoring, to develop the concept of a healthy weight. Fourth, on the basis of diet and exercise, if weight cannot be effectively controlled, it can be appropriately supplemented with weight loss medication, but reducing diet and increasing exercise is the basis of weight loss and cannot rely on medication.