Double lower extremity atherosclerosis with left-sided plaque formation is formed due to the accumulation of excess lipids in the blood within the arterial walls, and is mainly caused by hyperlipidemia, high blood pressure, and improper diet. 1. Hyperlipidemia: As age increases, elastic fibers in arterial vessels decrease. Hyperlipidemia leads to the accumulation of lipids, which accumulate within the walls of the arteries, forming atherosclerosis and complicating plaques. 2. High blood pressure: high blood pressure leads to accelerated blood flow, and accelerated blood flow will strengthen the impact on the blood vessel wall, and under the long-term influence of the gradual occurrence of damage, it can induce atherosclerosis. 3. Improper diet: Eating too much oil, salt and stimulating food regularly will damage the arterial wall, and LDL and triglyceride will be deposited under the endothelium of the blood vessels, resulting in atherosclerosis. It is recommended that patients quit smoking and drinking, go on a regular schedule, eat light food, and avoid oily, high-protein diets. The appearance of double upper extremity atherosclerosis and plaque formation, timely to the regular hospital for professional treatment.