Hepatitis B vaccination can be administered normally during menstruation and usually does not affect the efficacy of the hepatitis B vaccine. Hepatitis B vaccine is an agent used to prevent hepatitis B virus infection. When hepatitis B vaccination is administered, attention should be paid to whether there are any contraindications to hepatitis B vaccination, such as whether there is any allergic reaction to any component of the vaccine, whether there is any period of fever, whether there is any period of acute or chronic disease flare-ups, and whether there is any uncontrolled neurological disease, and so on. Hepatitis B vaccination contraindications do not require menstruating women, so it is believed that menstruating women can be vaccinated with hepatitis B vaccine and the efficacy of hepatitis B vaccine will not be affected. In addition, hepatitis B vaccine can be vaccinated during breastfeeding, but it is not recommended to be vaccinated during pregnancy. Personal care after vaccination is sufficient and usually causes no harm. Consult your physician for specific precautions regarding vaccination.