Feeling unable to breathe in the middle of the night may be caused by bronchial asthma, heart failure, sleep apnea syndrome, the patient should consult a doctor in a timely manner to clarify the cause of treatment. 1. Bronchial asthma: If you have been exposed to pollen, animal fur, seafood, etc., and have a history of allergy before sleeping in the middle of the night and feeling unable to breathe, you should consider bronchial asthma, and the patient will also have chest tightness, night sweats (sweating abnormally after falling asleep, and waking up after sweating stops) and other symptoms. 2. Heart failure: the elderly sleep in the middle of the night feel unable to breathe, and there is a basic heart disease, should be considered to be caused by heart failure, the patient will also have edema, cough and sputum and other symptoms. 3. Sleep apnea syndrome: snoring and apnea caused by repeated upper airway collapse and obstruction during sleep, patients will also have dry mouth in the morning, feel unable to breathe in the middle of the night, daytime sleepiness and other symptoms, such people can be relieved through surgery. Feeling unable to breathe in the middle of the night may also be caused by other diseases, such as lung tumors, acute heart attack, acute pulmonary edema, etc. It is recommended that the patient consult a doctor in time to make a clear diagnosis so as not to delay the condition.