Sudden twitching of the right hand is considered to be related to muscle spasm caused by overexertion, and epilepsy cannot be excluded due to the presence of central nervous system discharges, which needs to be evaluated according to the specific situation. If the twitching occurs due to excessive exercise or overexertion, muscle spasm is considered. If the twitching of the right hand occurs after emotional excitement, lack of sleep, staying up late, or mental tension, and the seizures are more frequent with certain impairment of consciousness or mental abnormalities, brain problems are considered and the possibility of epilepsy exists. It is necessary to improve the EEG examination in the neurology department of a second-grade hospital or above to observe whether there are abnormal fluctuations of brain waves, and also to improve the cranial MRI examination to exclude organic lesions of the head. If the muscle spasm is caused by overexertion, it is recommended to pay attention to rest first, and the symptoms will self-relieved.