Bilateral white matter ischemic foci in the parietal lobes are usually caused by atherosclerosis of the arteries supplying the brain. Atherosclerosis is a relatively common arterial disease that can occur in arteries throughout the body. If it occurs in the head and neck vessels and progresses gradually, it can lead to narrowing of the lumen of the vessels, causing chronic ischemic changes in the supplied brain, which may be manifested as ischemic changes in the brain when performing a cranial CT or MRI. The development of atherosclerosis is usually associated with many risk factors, such as smoking, hypertension, hyperlipidemia, diabetes mellitus, obesity, mental stress, sleep and so on. Relevant risk factors should be controlled in general to avoid the development and progression of atherosclerosis, thus preventing further progression of ischemic changes. When ischemic foci are found in the white matter of bilateral parietal lobes, prompt medical consultation is recommended.