Toothpaste burns the face is considered to produce contact dermatitis, should be treated by local medication, oral medication and other measures. 1. Local treatment: Since toothpaste is soluble in water. First, gently rinse with water to remove the toothpaste and avoid further damage. 2. Topical medication: zinc oxide ointment can be used externally for local protection. If the skin is not broken and there are no wounds, glucocorticoid medication, such as hydrocortisone ointment and compound dexamethasone ointment, can be applied; if there are secondary bacterial infections, antibiotic medication such as erythromycin ointment and mupirocin ointment can be used externally. 3. Oral medication: the main choice of antihistamine drugs. Commonly used antihistamines are loratadine and ebastine. It is recommended to go to the hospital for examination to clarify the cause of the disease, and the drugs need to be used under the guidance of professional doctors.