Crohn’s disease is different from common enteritis in terms of etiology, clinical manifestations and treatment modalities. 1. Etiology: the cause of Crohn’s disease has not been completely clarified, and it is considered to be the result of a combination of genetic, environmental, immune and other factors. Common enteritis is often caused by viruses, bacteria, parasites and other pathogenic microorganisms. 2. Clinical manifestations: Crohn’s disease starts insidiously and progresses slowly, and there may be abdominal pain, diarrhea, weight loss and other symptoms. Common enteritis can be divided into chronic and acute. Acute enteritis usually starts rapidly, with nausea, vomiting and diarrhea as the main symptoms, while chronic enteritis can have recurrent abdominal pain and diarrhea. 3. Treatment: Crohn’s disease can be treated with aminosalicylic acid preparations such as sulfasalazine, mesalazine, and glucocorticoids such as budesonide; common enteritis with bacterial infections can be treated with antibiotics such as ciprofloxacin, and viral enteritis generally does not require pathogenic treatment, and loperamide can be used to stop diarrhea in those with severe diarrhea. Patients with suspected Crohn’s disease or common enteritis are advised to go to the hospital.