Patients with high anti-thyroid peroxidase antibodies who have only high levels but normal thyroid function and no other symptoms usually do not need treatment, while those with abnormal thyroid function need to be considered for treatment. Antithyroid peroxidase antibodies are a common indicator of thyroid disease, and can be elevated in autoimmune thyroiditis, Graves’ disease, postpartum thyroiditis, atrophic thyroid, partial nodular goiter, and other conditions. If the patient only has elevated anti-thyroid peroxidase antibodies but no other abnormal indicators and clinical manifestations, normal thyroid function can be temporarily without treatment, regular review can be. However, if the patient is found to have hypothyroidism, hyperthyroidism, or other abnormalities of the thyroid function, treatment should be considered. In the case of high anti-thyroid peroxidase antibodies, it is recommended to go to the hospital and ask the doctor to take into account the specific situation to determine the cause of the disease.