The main chemical component of arsenic is arsenic trioxide, and accidental ingestion or suicide swallowing is the most common clinical cause of poisoning. Clinically, patients can often manifest serious digestive symptoms and neurological symptoms, such as nausea, vomiting, abdominal pain, diarrhea, accompanied by dizziness, perioral numbness, fatigue, limb spasms, and even coma. Severe cases can lead to death because of respiratory failure. In the treatment of patients should be as early as possible to induce vomiting and gastric lavage treatment, gastric lavage can be given to activated charcoal for gastric retention, at the same time can be given to the use of laxative salts in order to reduce the reabsorption of arsenic compounds, to promote their excretion, and as early as possible to give dithiopyr sulfonate, penicillamine and other special detoxification drugs to be used. In other treatments, the main symptomatic supportive treatment is to alleviate the corresponding clinical symptoms of the patients, and at the same time actively stabilize the internal environment of the patients, correct acid-base imbalance and ionic disorders. For patients with severe diseases, blood purification therapy and ventilator-assisted ventilation therapy can be supplemented to prevent and control acute renal failure, respiratory failure and other related complications.