IgA nephropathy is a chronic progressive disease, which is generally difficult to cure and can only be controlled. IgA nephropathy renal biopsy pathology shows IgA-based immune complex deposition in the glomerular thylakoid zone, with glomerular thylakoid cell proliferation and thylakoid stroma increase as the basic histologic changes, but its clinical manifestations are diverse, mainly manifested as hematuria, which may be accompanied by varying degrees of proteinuria, high blood pressure and impaired renal function, and so on. IgA nephropathy is difficult to be cured, it is a chronic progressive disease, and risk factor assessment is very important for the choice of treatment program. Risk factor assessment includes proteinuria, blood pressure and glomerular filtration rate. Reducing proteinuria and controlling blood pressure are the basis of treatment for IgA nephropathy, and commonly used drugs include chlorosartan, valsartan, candesartan, captopril, enalapril, and so on. Glucocorticosteroids such as methylprednisolone and prednisone, and immunosuppressants such as cyclophosphamide and azathioprine also play an important role in the treatment of IgA nephropathy. Patients with IgA Nephropathy should go to the hospital in time and receive standardized treatment under the guidance of professional physicians.