Pus in the nail groove can be sterilized locally with iodophor, and then an incision can be made to drain adequately, and anti-infection treatment can be carried out at the same time. Nail fissure pus can first use iodophor local disinfection, and then timely surgical treatment, longitudinal incision and drainage along the side of the nail fissure. Nail root abscess requires separation and extraction of part or even all of the nail, and care should be taken to avoid damage to the nail bed during surgery to facilitate nail regeneration. Finger nerve block anesthesia should not be used in the vicinity of the lesion to avoid spreading the infection. After incision and drainage, the nail should be disinfected and changed regularly. In addition, symptomatic anti-infection treatment can be used under the guidance of the doctor with broad-spectrum antibiotics, such as cefaclor, amoxicillin and so on. After the above comprehensive treatment, the pus in the nail groove inflammation can be gradually relieved.