Patients with irritable bowel syndrome are generally not allowed to drink alcohol. Irritable bowel syndrome is a gastrointestinal dysfunction disease, mainly manifested as abdominal pain, abdominal distension, accompanied by stool abnormalities, but there is no organic lesions. Ethanol, the main component of alcohol, is a strong stimulant, and if patients with irritable bowel syndrome drink alcohol, it is easy to stimulate the gastrointestinal mucosa, aggravate the symptoms of abdominal pain and bloating, and also easy to cause mucosal damage, erosion and even gastric hemorrhage, gastric perforation, and so on. Especially for patients with irritable bowel syndrome and are taking medication, ethanol may change the activity of certain drug enzymes, thus affecting the efficacy of drugs. Therefore, patients with irritable bowel syndrome should avoid drinking alcohol. It is recommended that patients with irritable bowel syndrome should be treated under the guidance of a doctor, and at the same time, they should develop good living and eating habits, avoid stimulating foods, and have bowel movements on time.