Patients with hyperthyroidism who do not have contraindications to isotretinoin can be treated with isotretinoin, but please follow your doctor’s instructions. Isotretinoin belongs to the group of retinoids and is able to be used for the treatment of polymerized acne or nodular cystic acne that is severe and for which other treatments have failed. Treatment with this drug is contraindicated in people who are allergic to this drug, overdose of vitamin A, hyperlipidemia, breastfeeding and pregnant women. Therefore, patients with hyperthyroidism who do not have any of these contraindications can be treated with isotretinoin. It should be noted that adverse reactions such as allergic reactions, palpitations and hyperlipidemia may occur after taking the drug. Patients who need to be treated with isotretinoin should be under the supervision of a doctor.