Hepatitis B DNA 3.900E+03 is usually indicative of positive hepatitis B virus DNA, which means that the patient has hepatitis B virus infection. The normal value of Hepatitis B virus DNA quantification is below 100IU/ml, and if the viral quantification is above 100IU/ml, it indicates that there is Hepatitis B carriage. For hepatitis B carriers, further liver function tests are needed. If there are abnormalities in liver function, including elevated aminotransferases and elevated bilirubin, it indicates a hepatitis flare-up, at which point hepatoprotective and antiviral therapy is recommended. The first-line recommended antiviral drugs are entecavir, tenofovir, and propofol tenofovir, which can effectively inhibit the replication of hepatitis B virus and slow down the development of liver fibrosis and cirrhosis, as well as reduce the incidence of hepatocellular carcinoma. If there is an elevation of ghrelin and ghrelin aminotransferase, it is considered to be the window period of viral replication. Active antiviral treatment is needed, and generally we can consider oral lamivudine or adefovir, or interferon injection for antiviral treatment. It is recommended that patients go to the hospital in time for the appropriate examination to clarify the cause of the disease and then symptomatic treatment. In daily life, we should have a regular diet, avoid prolonged smoking and drinking, and go to the hospital for regular checkups.