The combination of lacidipine and irbesartan is a more common type of combined medication in the clinic, which is smooth and effective in lowering blood pressure, and the medication should be taken under the guidance of a doctor for reasonable use.
Lacidipine is a dihydropyridine calcium channel antagonist antihypertensive drug (CCB), and its mechanism of action for lowering blood pressure is to block the L-type calcium channels on the vascular smooth muscle, inhibit the transfer of calcium ions into the cell, thus dilating arterial vasculature and lowering blood pressure.
Irbesartan is an angiotensin II receptor inhibitor (ARB), which dilates blood vessels and lowers blood pressure by selectively antagonizing the action of angiotensin II receptors.
Lacidipine and Irbesartan have different principles of action and different target points, so the combination of drugs can reduce the dose of a single drug and reduce side effects, which is more commonly used in the clinic and has a better effect.
Long-term application of lacidipine and irbesartan may cause adverse reactions such as flushing, edema, renal insufficiency, hyperkalemia, accelerated heart rate, etc. It is recommended to take the medication under the guidance of a doctor, and do not take the medication blindly, so as to avoid irreversible damage.