Atg for aplastic anemia major?



Atg can treat severe aplastic anemia.

Aplastic anemia is a bone marrow hematopoietic failure disorder that may be caused by different etiologies and mechanisms. Most of the causes of this disease are unclear and may be related to viral infections, chemical factors, and long-term exposure to X-rays and radionuclides. The disease is usually categorized as severe or non-severe based on the patient’s condition, blood counts, bone marrow picture and prognosis.

Allogeneic hematopoietic stem cell transplantation is the preferred treatment for severe aplastic anemia. However, for patients with severe aplastic anemia who are not suitable for allogeneic hematopoietic stem cell transplantation, they can be treated with immunosuppressants, and the commonly used drugs are Atg (anti-thymocyte globulin) and cyclosporine.

Allergy test should be done before using the drug, glucocorticoid should be used to prevent allergic reaction during the process of using the drug, and the intravenous infusion of Atg should not be too fast, which can be combined with cyclosporine to form a strengthened immunosuppression program to enhance the therapeutic effect.

The above medications should be used under the guidance of a doctor, avoid self-medication, so as not to cause adverse consequences.