Calf fracture is tibiofibular fracture, tibiofibular fracture like ants bite is generally a normal phenomenon of fracture, may also be multiple peripheral neuritis, restless leg syndrome and other diseases. 1. Normal phenomenon: tibiofibular fracture patients will appear swelling, pain, local deformity, dysfunction and other symptoms, if the patient combined with neurovascular injury, there will be calf and foot sensory deficits, limb numbness and other manifestations. 2. Multiple peripheral neuritis:The causes of multiple peripheral neuritis are numerous, common drugs, chemicals, heavy metals and so on. The patient will also have sensory disorder, motor disorder, autonomic disorder and other phenomena. 3. Restless Legs Syndrome:The cause of Restless Legs Syndrome is still unclear, and it is considered to be due to heredity or a variety of diseases and other factors. The main symptoms of patients are discomfort in the lower limbs, mainly ant-walking sensation, peristaltic sensation, etc., and the desire to move the legs. Patients who experience symptoms like ant bites after a tibiofibular fracture are advised to seek prompt medical attention for a definitive diagnosis.