Plateau reaction headache is caused by the inability to adapt to the low oxygen environment in the plateau area, which can be relieved by transferring to a lower altitude area, resting, medication and oxygen therapy. 1. Transfer to low altitude areas: the oxygen content is lower in higher altitude areas, if the plateau reaction headache persists, you can stop the activities in the plateau area, transfer to low altitude areas as soon as possible, and go to the hospital for diagnosis and treatment. 2. Rest: Mild pain may be caused by lack of oxygen in the brain, stopping physical activity and reducing the oxygen consumption of other systems can effectively relieve headaches. 3. Medication: Oral ibuprofen extended-release capsules can be taken as prescribed by the doctor to relieve the pain, ibuprofen has a better effect on relieving mild to moderate headaches. 4. Oxygen therapy: Oxygen therapy is the main treatment method, due to the plateau reaction headache is caused by the lack of oxygen in the brain, so through the nasal catheter or mask oxygen inhalation can be effective in relieving headache symptoms. Adaptive exercise under the guidance of a doctor before entering the plateau can effectively prevent plateau reaction. Ensuring carbohydrate intake and avoiding excessive physical activity after entering the plateau can also help prevent the occurrence of plateau reaction headache.