Spinal cerebellar degeneration, also known clinically as spinal cerebellar ataxia or hereditary spinal cerebellar ataxia, is essentially a genetic disease. The main cause of the disease is progressive degeneration of the cerebellum, spinal cord, brainstem, and neurons in the brain tissue, which results in core symptoms such as unsteady walking and slurred speech. There are more than 40 types of hereditary spinal cerebellar ataxias that have been genetically tested, and the most common clinical condition is spinal cerebellar ataxia type 3, known as SCA3. It is insidious and early detection depends on family members or patients’ observation of themselves, and early symptoms may be mistaken for arthritis or cervical spondylosis until they develop into slurred speech and blurred vision.