If osteoarthritis is the cause of the symptoms of pain on stretching the left leg, then Nimesulide or Glucosamine Hydrochloride tablets can be used as both have anti-inflammatory and pain relieving properties. If it is caused by other reasons, then it should not be used. Nimesulide belongs to non-steroidal anti-inflammatory drugs, which have antipyretic, analgesic and anti-inflammatory effects and can be used to relieve pain caused by osteoarthritis. The use of the drug can lead to stomach pain, heartburn, allergies, dizziness and other adverse reactions, and in severe cases can lead to gastrointestinal ulcers or bleeding. Note that it is contraindicated in case of allergy to NSAIDs, active peptic ulcers/bleeding and its history, severe liver and kidney impairment. Aminoglucose Hydrochloride Tablets are used to treat and prevent osteoarthritis and relieve patients from leg pain caused by arthritis. The use of the drug can lead to adverse reactions such as itchy rash, nausea, diarrhea, bloating and constipation. Note that it is contraindicated for those who are allergic to this product. Use with caution in patients with severe hepatic or renal insufficiency. Patients should go to the hospital and have the cause diagnosed by a professional physician, and then treat the cause of the disease, do not use the drug without authorization.