Physiological factors, facial muscle spasm, epilepsy, etc. are considered for facial twitching. 1. Physiological factors: the patient’s nervousness, poor sleep and other reasons will cause sympathetic nerve excitation, facial twitching and other symptoms can occur, through rest, improve the mood, the symptoms will gradually disappear. 2. Facial muscle spasm: this disease may be caused by mechanical stimulation, facial nerve compression or poor recovery from facial nerve paralysis, etc. In the early stage of the disease, it mainly manifests as eyelid fluttering, and gradually expands to the corners of the mouth and the entire facial muscles. 3. Epilepsy: This disease is caused by highly synchronized abnormal discharges of neurons in the brain, at the onset of which the patient may manifest facial convulsions, which may be accompanied by involuntary twitching of the limbs, and is diagnosed by combining with brain MRI and electroencephalography. Patients with facial twitching are advised to seek prompt medical attention to clarify the cause of the condition and under the guidance of a physician to carry out appropriate treatment to avoid further progression of the condition.