We usually refer to the three symptoms of frequent, urgent and painful urination as urinary tract irritation, and many people know that urinary tract irritation usually means a urinary tract infection. However, even if a patient with urolithiasis does not have a urinary tract infection, he or she may experience increased frequency of urination, urgency of urination, and sometimes painful urination. The main reasons for these symptoms of urinary tract irritation in patients with urolithiasis are as follows: When the stone descends from the kidney through the ureter to the intermural segment of the urinary bladder, it may be embedded here due to the physiological narrowing of the intermural segment of the bladder, and the innervation of the intermural segment is the same as that of the bladder triangle, so the stone can irritate the bladder triangle here, causing symptoms of frequent and urgent urination. Ureteral stone in the process of downward movement of symptoms of urinary frequency, urinary urgency, often indicates that the stone has reached the intermural segment of the ureter, the stone discharge is imminent. Bladder stones moving in the bladder directly irritate the bladder triangle, which can cause urinary frequency and urgency. When the stone is located at the bladder neck opening or in the urethra, the stone irritates the bladder neck opening or the outer opening of the urethra, causing urinary frequency, urgency or pain. Of course, if the urinary tract stones cause mechanical obstruction of the kidney or ureter, which prolongs urine retention, it will be combined with urinary tract infection. And the infection of either kidney or ureter may cause bacteria to flow into the bladder with urine, resulting in edema, congestion, inflammatory infiltration, and superficial ulceration of the bladder mucosa. When this bladder mucosa is stimulated by inflammation the symptoms of frequent urination, urinary urgency and painful urination will appear. Therefore, when urolithiasis patients appear urinary frequency, urinary urgency, indicating that the bladder or urethra is stimulated by direct finding objects or inflammation, should be timely to the hospital for examination and treatment.