Wounds with pus and holes often indicate that the wound is infected with inflammation, which requires timely consultation and treatment, disinfection, drainage, and medication if necessary. Wound pus with holes, the first thing to do is to debride the wound, scrape the tissue clean, and then use saline and 3% hydrogen peroxide to thoroughly clean the wound of pus, ooze, etc., and finally disinfected with iodine volts and set drainage strips, and then use sterile gauze bandages, regular dressing changes. In order to prevent infection, need to take amoxicillin, cefaclor, levofloxacin and other antibiotics; for malnutrition, should increase the high protein, vitamin food intake; due to chronic diseases, such as diabetes mellitus and other diseases, need to be strictly controlled. It is recommended that patients seek timely medical attention, follow the doctor’s instructions to standardize the treatment, do not blindly self-medication, so as not to aggravate the symptoms of the wound.