High urea creatinine can cause damage to various organs, as well as more severe nausea and vomiting symptoms, and can lead to severe electrolyte disturbances. Both urea and creatinine are indicators of kidney function, and if both are high, it indicates hyperalgesia. These toxins cannot be excreted and accumulate in the body, which will cause invisible damage to many organs. For example, when it affects the heart, it will cause uremic cardiomyopathy; when it affects the brain, it will cause uremic encephalopathy; when these toxins cause damage to the blood system, it will cause patients to become anemic. The accumulation of toxins in the digestive tract will lead to loss of appetite, nausea, vomiting, and inability to eat anything, which will lead to electrolyte disorders, and electrolyte disorders are likely to cause death. Of course, it should be emphasized that if urea and creatinine are only mildly elevated, the effects should be minor, but if they are moderately or even severely elevated, all the above-mentioned dangers may occur.