Diffuse pemphigus is baldness with multiple skin lesions, a psychogenic-dominant, autoimmune-related, non-scarring hair loss disorder that can occur on any part of the body. It is usually curable. Most cases of baldness can regenerate, but it can also reoccur, and the more extensive the hair loss and the longer the duration of the disease, the less chance of regeneration. Patchy baldness patients may be related to tension, anxiety, great work pressure, reduction of sleep, decreased immune function so that the scalp hair follicles immune problems, inflammation, allergies and other causes of load stress. Patients can usually recover completely through regular treatment. It is recommended that patients follow the doctor’s instructions to use topical drugs such as topical minoxidil to promote hair growth, baldness area can be used externally or injected glucocorticosteroids such as compound betamethasone injection to reduce inflammation around the hair follicle, for rapid and extensive alopecia, including total baldness and generalized baldness can be orally administered prednisone. In addition, it is recommended that patients with diffuse alopecia areata go to the hospital in time and follow the doctor’s instructions for active treatment to avoid delaying the condition.