With the progress of medical science and technology, children with precocious heart disease can live like normal people after active treatment. These treated children with precocious heart disease enter the childbearing age, or normal people have already given birth to children with precocious heart disease and want to have children again, they often worry that precocious heart disease will be hereditary, so will precocious heart disease be hereditary or not? Genetic refers to the phenomenon that parents and children are very similar in morphological structure and physiological function characteristics, many studies have proved that there is a clear trend of familial onset of precocious heart disease, the prevalence of precocious heart disease of siblings and children is 10-14 times higher than the general group of children born, parents have precocious heart disease, the prevalence of their children is 2%-5%, there are two children with congenital heart disease, the chance of re-occurrence The chance of reoccurrence can be as high as 10-15%. The occurrence of congenital heart disease in the same family can be the same type, but also different types. From these phenomena, congenital heart disease is related to genetics, there is a certain genetic tendency, but not a certain genetic pattern, can not be called genetic disease. Therefore, congenital heart disease has some heredity, not the main aspect of its pathogenesis.