Large B-cell lymphoma is known as diffuse large B-cell lymphoma, and specific symptoms include enlarged lymph nodes, decreased peripheral blood cells, enlarged spleen, etc.
1. Diffuse large B-cell lymphoma belongs to a group of non-Hodgkin’s lymphoma, and the typical clinical manifestations are painless progressive lymph node enlargement, splenomegaly, etc. Most patients usually consult the doctor for superficial lymph node enlargement, such as enlargement of cervical lymph nodes and axillary lymph nodes.
2. As the disease progresses, patients with diffuse large B-cell lymphoma may have anemia, decreased white blood cell and platelet counts and other manifestations of peripheral blood cell reduction, which is more obvious when the tumor cells invade the bone marrow. Patients may also have symptoms such as unexplained fever, night sweats, and emaciation.
It is recommended that patients with diffuse large B-cell lymphoma should consult the hematology department in time, complete bone marrow aspiration and biopsy to assess whether there is any invasion of bone marrow, complete PET-CT and other examinations to assess the extent of lesion involvement, stage the disease and evaluate the prognosis, formulate individualized treatment plan and actively treat under the guidance of physicians.